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Thomas C Vary Selected Research

Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)

9/2007Acute oral leucine administration stimulates protein synthesis during chronic sepsis through enhanced association of eukaryotic initiation factor 4G with eukaryotic initiation factor 4E in rats.
8/2007Regulation of muscle protein synthesis during sepsis and inflammation.
12/2006Cytokine-triggered decreases in levels of phosphorylated eukaryotic initiation factor 4G in skeletal muscle during sepsis.
2/2006IGF-I stimulates protein synthesis in skeletal muscle through multiple signaling pathways during sepsis.

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Thomas C Vary Research Topics

Disease

15Sepsis (Septicemia)
03/2011 - 11/2002
5Body Weight (Weight, Body)
11/2009 - 08/2007
4Atrophy
07/2011 - 12/2005
4Inflammation (Inflammations)
06/2010 - 11/2002
4Insulin Resistance
04/2009 - 09/2005
4Muscular Diseases (Myopathy)
05/2008 - 06/2004
4Abscess
12/2006 - 09/2003
3Obesity
01/2012 - 09/2007
3Resistance To Insulin-Like Growth Factor I
05/2010 - 03/2003
2Hyperglycemia
01/2012 - 12/2007
2Alcoholic Cardiomyopathy
04/2011 - 07/2010
2Muscular Atrophy (Muscle Atrophy)
10/2008 - 12/2005
2Neoplasms (Cancer)
01/2008 - 08/2007
2Weight Loss (Weight Reduction)
12/2005 - 12/2004
1Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left)
02/2012
1Cardiomegaly (Heart Hypertrophy)
02/2012
1Bacterial Infections (Bacterial Infection)
09/2010
1Glucose Intolerance
11/2009
1Tuberous Sclerosis (Bourneville's Disease)
10/2008
1Alcoholism (Alcohol Abuse)
06/2008
1Diabetes Complications
12/2007
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
12/2007
1Hypertrophy
12/2007
1Type 2 Diabetes Mellitus (MODY)
12/2007
1HIV Infections (HIV Infection)
08/2007
1Ischemia
09/2005
1Burns
04/2004
1Shock
12/2003
1Acidosis
12/2003

Drug/Important Bio-Agent (IBA)

24Proteins (Proteins, Gene)FDA Link
04/2011 - 11/2002
8Messenger RNA (mRNA)IBA
07/2011 - 06/2003
7Muscle Proteins (Muscle Protein)IBA
03/2011 - 06/2007
7Insulin-Like Growth Factor I (IGF-1)IBA
11/2009 - 06/2003
6Leucine (L-Leucine)FDA Link
06/2010 - 06/2004
6Eukaryotic Initiation Factor-4EIBA
09/2007 - 04/2004
5Amino AcidsFDA Link
11/2009 - 06/2004
4UbiquitinIBA
07/2011 - 12/2005
4Eukaryotic Initiation Factor-2B (Eukaryotic Initiation Factor 2B)IBA
03/2011 - 11/2002
4Peptide Initiation Factors (Initiation Factor)IBA
03/2011 - 11/2002
4Insulin (Novolin)FDA Link
11/2009 - 09/2007
4Eukaryotic Initiation Factor-4G (Eukaryotic Initiation Factor 4G)IBA
09/2007 - 02/2006
3Proteasome Endopeptidase Complex (Proteasome)IBA
07/2011 - 12/2005
3Phosphotransferases (Kinase)IBA
03/2011 - 11/2002
3TOR Serine-Threonine KinasesIBA
03/2011 - 06/2010
3CytokinesIBA
10/2008 - 09/2003
3Glucose (Dextrose)FDA LinkGeneric
12/2007 - 09/2005
3Insulin-Like PeptidesIBA
08/2007 - 06/2003
23-methylhistidineIBA
07/2011 - 11/2009
2Ribosomal Protein S6 Kinases (S6 Kinase)IBA
08/2007 - 11/2004
2GlucocorticoidsIBA
08/2007 - 12/2005
2Arginine (L-Arginine)FDA Link
12/2005 - 06/2004
2Glutamine (L-Glutamine)FDA Link
06/2004 - 12/2003
1Adrenergic Agents (Adrenergic Drugs)IBA
02/2012
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
02/2012
1EnzymesIBA
02/2012
1PolyaminesIBA
02/2012
1Isoproterenol (Isoprenaline)FDA LinkGeneric
02/2012
1Antipsychotic Agents (Antipsychotics)IBA
01/2012
1Lithium ChlorideIBA
03/2011
1LithiumIBA
03/2011
1Glycogen Synthase KinasesIBA
03/2011
1Glycogen Synthase Kinase 3 betaIBA
03/2011
1EndotoxinsIBA
09/2010
1Guanine NucleotidesIBA
08/2010
1LipopolysaccharidesIBA
06/2010
1Transaminases (Aminotransferases)IBA
05/2010
1Testosterone (Sustanon)FDA Link
11/2009
1Branched-Chain Amino AcidsIBA
04/2009
1Drinking WaterIBA
04/2009
1CholesterolIBA
04/2009
1trans-sodium crocetinate (crocetin)IBA
10/2008
1AICA ribonucleotide (ZMP)IBA
10/2008
1CorticosteroneIBA
05/2008
1Ethanol (Ethyl Alcohol)IBA
01/2008
1Mechanistic Target of Rapamycin Complex 1IBA
01/2008
1Mechanistic Target of Rapamycin Complex 2IBA
01/2008
1Phenylalanine (L-Phenylalanine)FDA Link
01/2008
1PhlorhizinIBA
12/2007
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2007
1Dietary ProteinsIBA
08/2007
1NitrogenIBA
08/2007
1Growth Hormone (Somatotropin)IBA
08/2007
1Ligases (Synthetase)IBA
12/2005
1Proteasome InhibitorsIBA
12/2005
1Mifepristone (RU 486)FDA Link
12/2005
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
12/2005
1Bortezomib (Velcade)FDA Link
12/2005
1PolyubiquitinIBA
12/2005
1Nitric Oxide (Nitrogen Monoxide)FDA Link
12/2005
1BuffersIBA
09/2005
1PalmitatesIBA
09/2005
1Indinavir (Crixivan)FDA Link
09/2005
1p38 Mitogen-Activated Protein KinasesIBA
12/2004
1Eukaryotic Initiation Factor-2 (EIF 2)IBA
04/2004
1Mitogen-Activated Protein KinasesIBA
12/2003
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
12/2003
12- (2- amino- 3- methoxyphenyl)- 4H- 1- benzopyran- 4- oneIBA
12/2003

Therapy/Procedure

1Castration
11/2009
1Intravenous Infusions
01/2008
1Nutritional Support (Artificial Feeding)
06/2004